Inner Beauty, GABALAGEN

 1. Product Name: Fermented GABA Collagen (GABALAGEN)

  • Ingredients: Low-molecular fish collagen
  • Appearance: Light yellowish-brown powder with characteristic flavor and without any off-flavor or off-odor

2. Index Ingredients

  • γ-Aminobutyric acid (GABA) content (mg/g): 100 (80–120% of labeled amount)
  • Glycine content (mg/g): 10 (80–120% of labeled amount)

3. Production Process

  • Two-step fermentation process using two patented strains (Lactobacillus brevis BJ20 & Lactobacillus plantarum BJ21)
  • Collagen is hydrolyzed into low molecular weight (275 Da) to maximize absorption while simultaneously generating GABA
  • Developed as a premium raw material

4. Significance (Regarding Stability)

  • Excellent pH stability and heat stability
  • 100% water-soluble, applicable to various formulations (beverages, powders, capsules)
  • Functionality for skin, sleep, and joint health verified through human clinical trials, animal experiments, and cell studies

5. Results of Molecular Weight and Functional Efficacy Analysis


6. In-vivo

 Skin Health-Improving Effects of Fermented GABA Collagen
  • GABALAGEN alleviates the increase in epidermal thickness caused by UV exposure.


Sleep Health-Improving Effects of Fermented GABA Collagen
  • GABALAGEN reduces wake time and increases total sleep and non-REM sleep.
    • The sleep-improving effect was confirmed by increased GABA receptor expression.

Joint Health-Improving Effects of Fermented GABA Collagen
  • GABALAGEN suppresses the mRNA expression of collagen-degrading enzymes in cartilage.

7. Human Clinical Trials

Effect of GABALAGEN on Skin Health Improvement Comparison 
  • Randomized, double-blind, placebo-controlled human clinical trial for evaluation research.
  • 24-week intake, randomized, double-blind, parallel-design, placebo-controlled study.


Effect of GABALAGEN on Sleep Health Improvement Comparison 
  • Randomized, double-blind, placebo-controlled human clinical trial for evaluation research.
  • 24-week intake, randomized, double-blind, parallel-design, placebo-controlled study.

Effect of GABALAGEN on Sleep Health Improvement Comparison 
  • Randomized, double-blind, placebo-controlled human clinical trial for evaluation research.
  • 24-week intake, randomized, double-blind, parallel-design, placebo-controlled study.







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Fermented Oyster Extract(FSO) for muscle strength improvement

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1. Product Name: Fermented Oyster Extract (FSO) (K-FDA : No. 2023-39) Ingredients: Oysters (Crassostrea gigas) Appearance: A yellowish-brown, particle-free powder with a unique flavor and no off-flavor or odor. 2. Index Ingredients γ-Aminobutyric acid (GABA) content (mg/g): 100 (80–120% of labeled amount) Taurine content (mg/g): 7.8 (80–120% of labeled amount) 3. Production Process Dual fermentation process using two patented strains (Lactobacillus brevis BJ20 & Lactobacillus plantarum BJ21) Functional components significantly enhanced compared to conventional raw materials, developed as a premium ingredient 4. Significance (Regarding Stability) Excellent pH stability High temperature stability 100% water-soluble, suitable for various formulations, including beverages, powders, and capsules 5.  In vivo  FSO reduces oxidative stress and improves muscle atrophy in dexamethasone-induced animal models · Confirmation of inflammation through tissue staining (M.E staining) · Conf...
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 "A multi-functional lacto-fermented oyster supplement with high GABA content that promotes height growth and bone health" Product of fermented organic oyster  with company patented lacto-fermentation process Oysters are a superfood packed with many nutrients · Are high in protein (50% on dry basis), essential vitamins ( B12 and D ) and important minerals ( Calcium, iron, zinc, phosphorus, selenium) · known for many health benefits including cardiovascular health, muscle growth, and bone health enhancement. · Are high in amino acid Taurine (4.2% on dry basis)- improve fatigue recovery stress relaxation Verification of FGO bone formation & growth promoting efficacy · Vetebrate Bone formation and Lengthening effect of Zebra fish (reference : Biomolecules 2019, 9, 711.) · Efficacy of strengthening femoral tissue and bone strength in osteoporosis RAT model (reference : Integr Med Res. 2020 Dec;9(4):100412.) Clinical trial study of the growth effect of fermented oyster ext...
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어린이키성장 개별인정형 원료, 유산균발효굴추출물(FGO)

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1. 제품명: 유산균발효굴추출물 (FGO) (제2024-26호) 원재료: 국내산 굴 (Crassostrea gigas) 성상: 고유의 향미가 있고 이미·이취가 없는, 황갈색의 입자성이 없는 분말 2. 지표성분 감마아미노부틸산 (γ-aminobutyric acid, GABA) 함량 (mg/g): 115 (표시량의 80~120%) 타우린( Taurine) 함량 (mg/g): 3.4 (표시량의 80~120%) 3. 생산 공정 특허균주 Lactobacillus brevis BJ20을 이용해 37℃에서 48시간 발효한 굴을 첨단 공정으로 정제·농축·분말화하여, 기존 원료 대비 기능성 성분을 획기적으로 강화한 프리미엄 소재 4. 유의성 (안정성 관련) pH 변화 안정성 우수 고온 안정성  100% 수용성, 음료·분말·캡슐 등 다양한 제형 적용 가능 5. In-vivo 뼈 형성과 성장 호르몬 수치 변화 : FGO 섭취는 성장 관련 유전자 발현 증가를 통해 뼈 형성·재생과 길이 성장을 촉진함. 뼈 형성 수치 변화 :  FGO 섭취는 Wnt/β-catenin 경로 활성화를 통해 뼈 형성을 촉진함. 난소절제 모델에서의 뼈 형성 및 골밀도 증가 :  FGO 섭취는 난소절제 모델에서 골밀도를 개선함. 6. 인체적용시험 - 어린이 키성장 - FGO 섭취가 소아 신장 성장에 미치는 효과 영향 및 안전성 비교 평가연구를 위한 무작위 배정, 이중눈가림, 대조군 비교 인체적용시험  24 주간 섭취, 무작위배정, 이중눈가림, 평행설계, 대조식품 비교 연구 1차 인체적용시험  2차 인체적용시험 - 뼈건강 - FGO 섭취가 뼈 건강에 미치는 영향 및 안전성 비교 평가연구를 위한 다기관, 무작위배정, 이중 눈가림, 대조군 비교 인체적용시험 24 주간 섭취, 무작위배정, 이중눈가림, 평행설계, 대조식품 비교 연구 7. 인증서 및 특허
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