Fermented Oyster Extract(FSO) for muscle strength improvement

1. Product Name: Fermented Oyster Extract (FSO) (K-FDA : No. 2023-39)

• Ingredients: Oysters (Crassostrea gigas)
• Appearance: A yellowish-brown, particle-free powder with a unique flavor and no off-flavor or odor.

2. Index Ingredients

• γ-Aminobutyric acid (GABA) content (mg/g): 100 (80–120% of labeled amount)
• Taurine content (mg/g): 7.8 (80–120% of labeled amount)

3. Production Process

• Dual fermentation process using two patented strains (Lactobacillus brevis BJ20 & Lactobacillus plantarum BJ21)
• Functional components significantly enhanced compared to conventional raw materials, developed as a premium ingredient

4. Significance (Regarding Stability)

• Excellent pH stability
• High temperature stability
• 100% water-soluble, suitable for various formulations, including beverages, powders, and capsules

5.  In vivo 

• FSO reduces oxidative stress and improves muscle atrophy in dexamethasone-induced animal models

· Confirmation of inflammation through tissue staining (M.E staining)

· Confirmation of gastrocnemius muscle weight and thickness

· Confirmation of gastrocnemius muscle thickness through tissue staining (H&E staining) 

6. Human Clinical Trial

• Effects of FSO Intake on Body Composition, Muscle Strength, and Serum Muscle Growth Factors in Middle-Aged Women
• 8-week intake, randomized, double-blind, parallel-design, placebo-controlled human clinical trial

FSO intake shows a significant increase in muscle strength 

compared to the placebo group